At the end of 2021, the total area of protected natural areas in the republic amounted to 3457.8 thousand hectares.

When analyzing this indicator by regions, 74.9% of the total area fell on the Republic of Karakalpakstan, 18.6% - on the Tashkent region, 2.4% - on the Kashkadarya region and 2.0% - on the Jizzakh region.